In 1977, a small group of people concerned about animal welfare issues in Ozaukee County formed the Ozaukee Humane Project. Their main focus was to provide educational programs for the area schools. As this group increased in number and received some community recognition and support, the name was changed to the Ozaukee Humane Society. In 1982, an office was established in the Manchester Mall in Grafton. This office, staffed by volunteers, was a referral service with a lost and found hotline for stray animals. Membership in the organization continued to grow and over the next four years plans were developed to create an Ozaukee Humane facility. This plan became a reality in October 1988 when the shelter in Grafton opened its doors.

In 2004, OHS merged with the Wisconsin Humane Society to expand the lifesaving opportunities available to animals in Ozaukee County.

In March 2011, we opened the doors to the new shelter, the Wisconsin Humane Society Ozaukee Campus: Victoria Wellens Center. Located in Saukville off Highway 33, the new, "green" shelter is four times the size of the old shelter and offers extensive services to the animals and residents of Ozaukee County, including: